Antigens and Antibodies

The clumping of red blood cells when testing blood compatibility or resulting from a transfusion reaction is called agglutination. This phenomenon is due to a reaction between red blood cell surface molecules called antigens (an'-ti-jenz) (formerly called agglutinogens) and protein antibodies (formerly called agglutinins) carried in the plasma. Although many different antigens are associated with human erythrocytes, only a few of them are likely to produce serious transfusion reactions. These include the antigens of the ABO group and those of the Rh group. Avoiding the mixture of certain kinds of antigens and antibodies prevents adverse transfusion reactions.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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