Future directions in alcohol dehydrogenasecatalyzed reactions

Jon D. Stewart

Department of Chemistry, University of Florida, Gainesville, FL, USA Abstract

The number of available dehydrogenases has exploded with the appearance of hundreds of complete genome sequences. The vast number of potential substrate- and stereospecificities represented in this resource has the potential to revolutionize the use of dehydrogenases in organic synthesis, but only if methods for harnessing and applying their power can be developed. Achieving this goal will require advances in computational, analytical and protein-screening technologies.

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