The constituent, gymnemic acid, inhibits the ability to taste sweetness in animal models (Fushiki et al 1992, Harada & Kasahara 2000, Kurihara 1969, 1992) and humans (Frank et al 1992). In humans, the administration of 5 mmol/L gurmarin to the tongue raised the threshold ability to taste sucrose from 0.01 mol/L to 1 mol/L for several hours. It is suggested that gurmarin acts on the apical side of the taste cell, possibly by binding to the sweet taste receptor protein (Miyasaka & Imoto 1995).
Was this article helpful?
Curb Sugar Cravings Once And For All With These Powerful Techniques. Sugar sensitive people might be low in specific neurochemicals that help us feel calm, centered, confident, and optimistic. Sugar is a drug that temporarily makes the sugar sensitive feel better, but with damaging consequences.