Antineoplastic activity has been observed for fenugreek in the Ehrlich ascites carcinoma model in mice (Sur et al 2001). Protodioscin, purified from fenugreek, has also exhibited antineoplastic activity on human leukaemia cell lines in vitro (Hibasami et al 2003). Although fenugreek contains coumarin constituents, a placebo-controlled study found that it does not affect platelet aggregation, fibrinolytic activity or fibrinogen (Bordia et al 1997). Traditionally it is thought to promote lactation in nursing mothers and act as a general tonic.
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