As chromium has a role in maintaining carbohydrate and lipid metabolism, and potentiating insulin action, it has been suggested that chromium supplementation may have effects on body composition, including reducing fat mass and increasing lean body mass (Vincent 2003).
A meta-analysis of RCT concluded that chromium picolinate elicited a relatively small effect compared with placebo for reducing body weight (Pittler et al 2003). One study, however, did show promising results using 200^g chromium bound to niacin three times daily (total 600 ^g/day) with moderate exercise. At these high doses, while overall reduction in body weight was similar for both the chromium and placebo groups, total fat loss was more significant in the chromium group, suggesting a muscle sparing effect (Crawford et al 1999).
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