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The role of carnitine in fatty acid metabolism suggests a potential role in hyperlipidaemia. Several studies have indicated that oral l-carnitine significantly reduces lipoprotein-a levels; however, effects on other lipids are inconsistent, l-Carnitine (2 g/day) significantly reduced serum lipoprotein-a levels in 77.8% of subjects receiving active treatment after 12 weeks, according to one placebo-controlled, double-blind randomised study. No significant change was observed in other lipid parameters (Sirtori et al 2000). l-Carnitine (2 g/day) was also shown to significantly lower lipoprotein-a levels at 3 and 6 months in a double-blind placebo-controlled trial of 94 hypercholesterolemic patients with newly diagnosed type 2 diabetes (Derosa et al 2003). In a trial of children with hyperlipidaemia, lipoprotein-a levels were only reduced in those with type II homozygotes and other lipid parameters worsened (Gunes et al 2005). l-Carnitine has also been shown to decrease apolipoprotein B levels in paediatric peritoneal dialysis patients (Kosan et al 2003). A study of elderly people taking l-carnitine (2 g twice daily) demonstrated improvements in total serum cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, apoproteins A1 and B at 30 days (Pistone et al 2003). Animal studies have also suggested the potential for carnitine to lower triglyceride levels (Eskandari et al 2004); however, clinical trials using oral doses in type 2 diabetes have indicated an increase in triglycerides (Rahbar et al 2005). Further human trials are required to confirm which population groups may benefit from carnitine supplementation.

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Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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