According to an open study, a dose of 330 mL cranberry juice can increase the excretion of oxalic acid and uric acid (Kessler et al 2002).
Results from human studies are contradictory, but overall suggest no significant change to urinary pH at doses less than 330 mL daily. A crossover study of 27 patients with indwelling urinary catheters and chronic bacteriuria showed no change to urinary pH (Nahata et al 1982), as did a double-blind study of 1 53 women (Avorn et al 1994). One small, open study involving 12 healthy subjects found that 330 mL cranberry juice reduced urinary pH (Kessler et al 2002).
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