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Eight patients with reactive hypoglycaemia were given chromium chloride (equivalent to 200 fjg chromium) for 3 months in a double-blind crossover study. Chromium supplementation significantly improved blood sugar regulation, insulin binding to receptors and red blood cells, and alleviated symptoms of hypoglycaemia (Anderson et al 1987).

A double-blind crossover study using chromium chloride (equivalent to 200 fjg/day elemental chromium) for 8 weeks found a significant improvement in glycaemic control in subgroups where the 2-hour glucose level was > 10% above or below the fasting level (Bahijri 2000). In these subgroups chromium supplementation resulted in a 2-hour mean not significantly different to the fasting mean, suggesting an amphoteric effect on glycaemic control.

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