A 2002 study in mice found that topical application of grapeseed PCs considerably accelerate wound contraction and closure and provided additional support during the wound healing process (Khanna et al 2002).
Chloasma Chloasma is a condition characterised by hyperpigmentation and is generally considered recalcitrant to treatment. Proathocyanidin-rich GSE successfully reduced hyperpigmentation in women with chloasma after 6 months of oral treatment according to an open study involving 12 subjects (Yamakoshi et al 2004). The study continued for another 6 months but failed to find an additional improvement with further use. The researchers suggested that a preventative effect may be possible with long-term oral GSE when used in the months prior to summer.
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