Strong laxatives such as aloe latex are contraindicated in children. Avoid in patients with known hypersensitivity to aloe or with nausea, vomiting or signs and symptoms of gastrointestinal obstruction. Avoid excessive use and long-term use (more than 2 weeks), as potassium losses may occur, which may alter cardiac electrophysiology. Use with caution in people with thyrotoxicosis.
A case study of depression of thyroid hormones in a woman taking Aloe vera juice has been reported (Pigatto & Guzzi 2005). The patient consumed 10 mL daily for 11 months and laboratory testing showed reduced levels of thyroxine and triiodothyonine. Levels returned to normal progressively after discontinuing the aloe juice and the patient achieved full clinical remission after 16 months. Reduced serum levels of the thyroid hormones T3 and T4 have been reported for Aloe vera in vivo (Kar etal 2002).
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