Gentian root preparations have not been significantly investigated under clinical trial conditions, so evidence is mainly derived from traditional, in vitro and animal studies. DYSPEPSIA AND FLATULENCE
The considerable bitter taste of gentian provides a theoretical basis for its use in dyspepsia and flatulence for which increased saliva and gastric acid secretion would be beneficial. Commission E and ESCOP approve its use for this indication (Blumenthal et al 2000, ESCOP 2003).
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