As it passes through the digestive tract, chitosan binds to ingested fat, bile acids, cholesterol and other lipids, preventing their absorption. The complexes that form between chitosan and various fats are then excreted in the faeces. A human study investigating whether the effect is clinically significant found that a dose of 4.5 g/day, © 2007 Elsevier Australia
taken in divided doses 30 minutes before meals, trapped only negligible amounts of fat as measured by fat excretion in stools (Gades & Stern 2003).
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