Both an aqueous extract and a gel fraction isolated from the seeds demonstrated significant ulcer-protective effects in vivo (Pandian et al 2002). The seed fractions given orally to test animals provided dose-dependent gastric protection against the effects of ethanol that was as potent as that of omeprazole. Furthermore, histological studies found that the soluble gel fraction was significantly more protective than omeprazole. Preliminary research suggests that the polysaccharide composition and/or flavonoid components of the gel are responsible for the gastroprotective and antisecretory activities of the seeds.
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