Antimicrobial

Hydro-alcoholic extracts have been shown to have antibacterial, antiviral and antifungal activities. The in vitro antifungal activity of calendula flower extracts has been investigated against Aspergillus niger, Rhizopus japonicum, Candida albicans, C. tropicalisand Rhodotorula glutinis. Calendula extract showed a high degree of activity against all fungi and the inhibitory effect was comparable to that of standard antifungals (Kasiram et al 2000). A flower extract has been shown to inhibit trichomonas. The oxygenated terpenes are thought to be the main active compounds (Gracza & Szasz 1968, Samochowiec et al 1979). A 70% hydro-alcoholic extract demonstrated virucidal activity against influenza virus and suppressed the growth of HSV (Bogdanova et al 1970). Calendula flower extract has also been shown to possess anti-HIV activity in vitro (Kalvatchev et al 1997).

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