Antiinflammatory

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Chondroitin exerts an anti-inflammatory action with an inhibitory effect over complement (Pipitone 1991). In an in vitro study of bovine cartilage, chondroitin alone and in combination with glucosamine was found to regulate gene expression and synthesis of NO and PGE2, suggesting a basis for its anti-inflammatory properties (Chan et al 2005). Chondroitin sulfate has been found to increase the levels of antioxidant enzymes and reduce inflammation and cirrhosis of liver tissue in an ovariectomised rat model, suggesting that it enhances antioxidant activity (Ha 2004).

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