Altering Neurotransmitter Activity

Albizia has an influence on GABA, serotonin and dopamine levels, according to in vivo studies (Chintawar et al 2002, Kasture et al 2000). It appears that different fractions within the herb exert slightly different effects on neurotransmitters. In one study, a saponin-containing fraction from the extract of dried leaves of Albizia was shown to decrease brain concentrations of GABA and dopamine, whereas serotonin © 2007 Elsevier Australia

levels Increased. Another study that tested the methanollc fraction of an ethanollc extract of Albizia leaves found that It raised brain levels of GABA and serotonin (Kasture et al 2000). Additionally, anticonvulsant activity has been demonstrated In vivo for this fraction.

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