An open study of 117 subjects with different forms of acne found that after 6 weeks' treatment with a 0.2% dried extract of Vitex agnus-castus and a topical disinfectant, 70% of cases experienced total resolution with the highest success rates reported for acne vulgaris, foilicularis and excoriated acne (Amann 1975). A group that was not treated with the herb took 30-50% longer to achieve similar results. Although encouraging, it is difficult to determine the contribution of vitex treatment to these results. Until controlled studies using vitex as a stand-alone treatment are conducted, the herb's role in this condition is still uncertain.
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