• Generally 100-1 50 mg/day has been used for conditions such as congestive cardiac failure (Mortensen et al 1990), hypertension, neurological disease, performance enhancement, periodontal disease (Wilkinson et al 1975).
• As preparation for cardiac surgery: 100-300 mg/day for 2 weeks before surgery followed by 100 mg/day for 1 month after surgery has been used (Judy et al 1993, Coenzyme Q10 308
Rosenfeldt et al 2002, 2005); 30-60 mg taken for 6 days before surgery has also been found to be effective (Tanaka et al 1982).
• Angina pectoris: 60-600 mg dally
• Chronic obstructive pulmonary disease: 50-90 mg dally
• Huntington's chorea: 600 mg dally
• Parkinson's disease (< 12,000 mg/day) (Shults et al 2002) ADVERSE REACTIONS
CoQ10 appears relatively safe and non-toxic and is extremely well tolerated. Dizziness, nausea, epigastric discomfort, anorexia, diarrhoea, photophobia, irritability and skin rash occur in less than 1 % of patients. This tends to occur with higher doses (>200 mg/day).
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