Withdrawal effects

These develop within 12 hours of ceasing regular usage. Maximum withdrawal symptoms usually occur between 36 and 72 hours.

• anxiety and panic

• irritability

• chills and shivering

• excessive sweating

• loss of appetite, nausea (possibly vomiting)

• lacrimation/rhinorrhoea

• tiredness/insomnia

• muscle aches and cramps

• abdominal colic

A secondary abstinence syndrome is identified 5 at 2 to 3 months and includes irritability, depression and insomnia.

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