Longterm problems

After 3-5 years of levodopa treatment side effects may appear in about one half of patients: 5

• involuntary movements—dyskinesia (use lower dose + pergolide)

• end of dose failure (reduced duration of effect to 2-3 hours only)

• 'on-off phenomenon (sudden inability to move with recovery in 30-90 minutes)

• early morning dystonia, e.g. clawing of toes (due to disease—not a side effect); management of motor problems summarised in Table 29.6 .

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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