Hours

Codeine Oxycodone

6G mg

Endone (oral) Proladone (rectal)

6-12

1G mg 1G mg

Methadone variable 8-24

15 mg

Dextromoramide (Palfium) 2 Fentanyl (transdermal) 72

2G mg 1GG mg

It is also useful for symptom control when there is a need for a combination of drugs, e.g. for pain, nausea and agitation. It may avoid bolus peak effects (sedation, nausea or vomiting) or trough effects (breakthrough pain) with intermittent parenteral morphine injections.

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