History

The history may indicate the nature of the problem:

• iron deficiency: inadequate diet, pregnancy, GIT loss, menorrhagia, NSAID and anticoagulant ingestion

• folate deficiency: inadequate diet especially with pregnancy and alcoholism, small bowel disease

• Vitamin B12 deficiency: previous gastric surgery, ileal disease or surgery, pernicious anaemia, selective diets, e.g. vegetarians, fad

• haemolysis: abrupt onset anaemia with mild jaundice

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