A hallmark of early stage CRF is a non-specific history and examination, and the diagnosis is very difficult in the absence of a known past history of renal disease. The diagnosis can be established only by renal function tests. Symptoms from CRF are rare unless the creatinine clearance is less than 20% of normal and only become common when less than 10% of normal.
In patients with chronic renal disease, symptomatic uraemia may be precipitated by prerenal factors such as fluid loss from vomiting or diarrhoea, infection, antibiotic therapy especially tetracyclines, or increasing hypertension.
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...