Haemolytic anaemias are relatively infrequent. The more common of the congenital ones are hereditary spherocytosis and deficiencies of the red cell enzymes, pyruvate kinase and G6PD, although most cases of G6PD deficiency haemolyse only when the patient takes oxidant drugs such as sulphonamides or eats broad beans—'favism'.

Acquired haemolytic anaemias include those of the newborn due to maternal haemolytic blood group antibodies passing back through the placenta to the foetus, and adult anaemias due to drug toxicity or to acquired autoantibodies. About half of the latter are 'idiopathic' and half associated with non-Hodgkin's lymphomas, and the anaemia may be the presenting sign of lymphoma. Some of these antibodies are active only at cool temperatures—cold agglutinin disease; others act at body temperature and are the more potent cause of autoimmune haemolytic anaemia.

Dealing With Back Pain

Dealing With Back Pain

Deal With Your Pain, Lead A Wonderful Life An Live Like A 'Normal' Person. Before I really start telling you anything about me or finding out anything about you, I want you to know that I sympathize with you. Not only is it one of the most painful experiences to have backpain. Not only is it the number one excuse for employees not coming into work. But perhaps just as significantly, it is something that I suffered from for years.

Get My Free Ebook

Post a comment