Coagulation disorders

The features are:

• ecchymoses

• haemarthrosis and muscle haematomas

• usually traumatic and delayed

The inherited disorders such as haemophilia A and B are uncommon and involve deficiency of one factor only. The acquired disorders such as disseminated intravascular coagulation (DIC) occur more commonly and invariably affect several anticoagulation factors (Table 35.6).

Table 35.6 International nomenclature of clotting factors

Factor Common synonyms

I

Fibrinogen*

II

Prothrombin*

III

Thromboplastin

IV

Calcium*

V*

Proaccelerin

VI

No longer used

VII*

Antihaemophilic factor Antihaemophilic globulin

IX* Christmas factor, plasma thromboplastin component

X* Stuart-Prower factor

XI* Plasma thromboplastin antecedent

XII Hageman factor, contact factor

XIII Fibrin stabilising factor

Common terminology in use indicated by *

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