Clinical features

young to middle-aged men constitutional symptoms: fever, malaise, myalgia, weight loss migratory arthralgia or polyarthritis subcutaneous nodules along arterial lines livedo reticularis and skin ulcers renal impairment and hypertension cardiac disorders: arrhythmia, failure, infarction diagnosis confirmed by biopsy or angiogram

ESR raised treatment with corticosteroids and immuno-suppressants death is usually from renal disease hypertension arthnt.s ulcer hypertension arthnt.s ulcer

General malaise we:çjhc loss fev^r

Cardiac myocardial infarction

□"rhvtfirr.ia hiart Fa: lure

Lungs pleurisy asthma

Renal glomerulonephritis nodules

— livedo reticularis

Fig. 28.6 Clinical features of polyarteritis nodosa

General malaise we:çjhc loss fev^r

Cardiac myocardial infarction

□"rhvtfirr.ia hiart Fa: lure

Lungs pleurisy asthma

Renal glomerulonephritis nodules

— livedo reticularis

Fig. 28.6 Clinical features of polyarteritis nodosa

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