Antimicrobial regimen for nonpregnant women

Multiple dose therapy preferred to single dose therapy.

• use for 5 days in women (trimethoprim— 3 days).

• use for 10 days in women with known UT abnormality.

o trimethoprim 300 mg (o) daily for 3 days or o cephalexin 500 mg (o) 12 hourly or o amoxycillin/potassium clavulanate 250/125 mg (o) 8 hourly (preferred agent) or o norfloxacin 400 mg (o) 12 hourly for 3 days (if resistance to above agents proven)


• Avoid using important quinolones—norfloxacin or ciprofloxacin—as first-line agents

• Co-trimoxazole is not first line because it has no advantage over trimethoprim and has more side effects.

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