In 1964, Gallagher and Geschickter57 reported several experimental and clinical in vivo applications of commercial gold leaf. They used it for haemostasis and prevention of adhesion between dura and brain. Later, in the same year, Kanof58 used the gold leaf successfully in treating cutaneous ulcers of the lower extremities. Porter et al59 evaluated the use of gold leaf on mongrel dogs, by covering experimentally induced hepatic defects with the foil. Films with thickness of
0.0000036 and 0.0000072 inches were successfully used in transected hepatic surfaces in every case, and haemostasis was achieved. In 1968, Dardik et al..60 used the foil on renal hilar vessels of rats, with good results.
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