Conformational Studies

A detailed appreciation of the biological function of a molecule requires that its conformation be understood. Therefore, in recent years a great deal of effort has been directed toward elucidating the solution conformation of oligosaccharides [92]. The work, however, has been heavily focused on oligopyranosides. At the same time, a wealth of information detailing the conformation of furanose rings in nucleotides and nucleic acids has accumulated [93]. However, except for sucrose [94,95], only recently have conformational investigations of oligosaccharides containing furanose residues been reported [96,97]. Outlined in this section are some recent investigations that have explored the solution conformation of methyl a-d-arabinofuranoside and oligosaccharides containing a-d-arabinofuranosyl residues.

Figure 17 Synthesis of 62: IDCP, iodine dicollidine perchlorate; TBDPS, r-butyldiphen-vlsilvl.
The Sugar Solution

The Sugar Solution

Curb Sugar Cravings Once And For All With These Powerful Techniques. Sugar sensitive people might be low in specific neurochemicals that help us feel calm, centered, confident, and optimistic. Sugar is a drug that temporarily makes the sugar sensitive feel better, but with damaging consequences.

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