Oxytocin Pitocin

Actions: produces rhythmic uterine smooth muscle contractions by increasing sodium permeability; cause vasodilation of smooth muscle (renal, coronary, and cerebral); stimulates breast milk flow during nursing.

Indications: postpartum hemorrhage, uterine atony, augment labor.

Dose (induction of labor): adult: 0.001-0.002 units/minute IV, increase by 0.001-0.002 units every 15-30 minutes until contraction pattern has been established; max dose of 20 milliunits/min. Dose (postpartum bleeding): adult: 10-40 units IV (mix 10-40 units in 1000 mL IVF) at a rate to control uterine atony; 10 units IM. Clearance: tissue metabolism, renal elimination. Adverse effects: may cause uterine tetany and rupture, fetal distress, anaphylaxis; IV bolus can cause hypotension, tachycardia, dysrhythmia.

Was this article helpful?

0 0
Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

Get My Free Ebook

Post a comment